Arizona Cardinals at San Francisco 49ers: kickoff time, TV coverage, and streaming options
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The San Francisco 49ers (2-0) welcome the Arizona Cardinals (1-1) to Levi’s Stadium on Sunday, September 21, 2025, for a key NFC West clash. San Francisco has looked dominant early, leaning on its balanced offense and suffocating defense, while Arizona is trying to prove it can hang in one of the league’s toughest divisions. The matchup also revives a divisional rivalry that often produces close, physical games, and could play an early role in shaping the NFC West race. Kickoff is set for 4:25 PM ET / 1:25 PM PT, with regional coverage on FOX.
Game information: Arizona Cardinals at San Francisco 49ers
| Category | Details |
| Date | Sunday, September 21, 2025 |
| Time | 4:25 PM ET / 1:25 PM PT |
| Venue | Levi’s Stadium, Santa Clara, CA |
| TV (Primary Network) | FOX |
| Channel Guide | DirecTV: 219 • Dish: Varies by region • Comcast/Xfinity: Varies by region • Spectrum: Varies by region • Verizon Fios: Varies by region |
| Stream | FOX Sports app (TV provider login), NFL+ (mobile/tablet in-market only), live TV streaming services (YouTube TV, Hulu + Live TV, Fubo, Sling TV with FOX in select markets) |
| Radio | Cardinals: Arizona Sports 98.7 FM / La Indiscreta 106.7 FM (Spanish) • 49ers: KNBR 680 AM, KSAN 107.7 FM |
| Coverage | Regional – coverage map not yet available; check 506 Sports closer to kickoff. Home-market affiliates: KSAZ-TV FOX 10 Phoenix, KTVU FOX 2 San Francisco. |
Where to watch Arizona Cardinals vs San Francisco 49ers US viewing options
The Week 3 matchup between the Arizona Cardinals and San Francisco 49ers will air on FOX as part of the network’s Sunday afternoon regional coverage. Fans in the Phoenix and Bay Area home markets are guaranteed local broadcasts on their FOX affiliates — KSAZ-TV FOX 10 Phoenix and KTVU FOX 2 San Francisco. Viewers in other regions may receive a different game depending on FOX’s assignments. Since this is not a national broadcast, fans outside the home markets should check the 506 Sports coverage map closer to kickoff to confirm whether Cardinals–49ers will be shown in their area.
What channel is Arizona Cardinals vs San Francisco 49ers on?
Cable and satellite subscribers who receive FOX can watch the Cardinals–49ers game live on TV. The broadcast will also be available via the FOX Sports app or FOXSports.com by logging in with your TV provider credentials.
In the home markets, the game will air on the local FOX affiliates: KSAZ FOX 10 Phoenix for Cardinals fans, and KTVU FOX 2 San Francisco for 49ers fans. These stations guarantee coverage within their respective DMAs. Viewers outside Arizona and Northern California may see a different matchup depending on FOX’s regional broadcast schedule – the official 506 Sports coverage map will confirm which regions get this game closer to kickoff.
Channel information by provider:
- DirecTV: game airs on your local FOX affiliate (KSAZ in Phoenix, KTVU in San Francisco). Some games may also use overflow channel 719 with NFL Sunday Ticket.
- Dish: local FOX affiliate; channel numbers vary by ZIP code.
- Xfinity / Comcast: FOX airs on the local affiliate; numbers vary.
- Spectrum: local FOX affiliate.
- Verizon Fios: FOX is available through the local affiliate, but placement varies by region.
Fans in the Phoenix and Bay Area markets can also watch the game for free over the air (OTA) with a digital antenna. Tune to FOX 10 in Phoenix or FOX 2 in San Francisco to catch the broadcast without a subscription.
How to watch Arizona Cardinals vs San Francisco 49ers on mobile phone/tablet
NFL+ is the NFL’s official streaming service for fans who want to watch games on mobile devices. The platform works on smartphones and tablets, providing access to live local and primetime games within your market. For Week 3, that means fans in Arizona and the Bay Area can stream Cardinals vs 49ers directly on their phones or tablets.
- NFL+ ($6.99/month): Includes live local and primetime games on mobile and tablet devices, plus live audio for every game.
- NFL+ Premium ($14.99/month): Adds full-game replays, condensed game versions, and access to the All-22 coaches film.
Restrictions to note: NFL+ does not include out-of-market Sunday Afternoon games, and it cannot be cast or mirrored to a TV. The service is designed as a supplementary option, not a full replacement for cable or streaming packages. Fans outside the home markets will need NFL Sunday Ticket or another out-of-market solution.
How to watch Arizona Cardinals vs San Francisco 49ers without cable
Cord-cutters can watch Cardinals vs 49ers on several live TV streaming platforms that carry FOX. Local affiliate availability depends on your ZIP code, so it’s important to confirm coverage before signing up.
- YouTube TV — $72.99/month. Includes FOX in most U.S. markets, covering both Phoenix and San Francisco. The service also offers unlimited DVR storage, making it easy to record games.
- Hulu + Live TV — $82.99/month. Offers FOX in most markets, including Arizona and Northern California. Subscriptions also include Disney+ and ESPN+ at no extra cost. Local FOX access varies by ZIP code.
- Fubo — Starting at $79.99/month. Carries FOX, CBS, NBC, and ABC in many markets, along with a wide range of Spanish-language sports channels.
- Sling TV (Blue) — $46/month. Includes FOX in select markets, such as Phoenix and San Francisco, but does not carry CBS at all. Availability is limited.
Reminder: FOX access is tied to your local affiliate. Always confirm channel availability using the provider’s lookup tool before subscribing to ensure the game is included in your package.
How to watch Arizona Cardinals vs San Francisco 49ers with an over-the-air antenna
Fans in the home markets can watch Cardinals vs 49ers for free with a digital antenna, since the game will be broadcast on FOX. In Phoenix, the matchup will air on KSAZ FOX 10, while Bay Area viewers can tune in to KTVU FOX 2 San Francisco. Over-the-air television does not require a subscription, but reception depends on your distance from the transmitter and the quality of your antenna.
OTA coverage only works if you are within range of the local broadcast signal. Viewers outside Arizona and Northern California may receive a different FOX game due to regional broadcast rules. To confirm availability, check the FCC DTV reception maps, use the AntennaWeb station finder, or review the 506 Sports coverage maps once they are released for Week 3.
How to listen to Arizona Cardinals vs San Francisco 49ers on a radio
Arizona Cardinals Radio
The Cardinals’ flagship station is Arizona Sports 98.7 FM, with play-by-play from Dave Pasch, analysis from Ron Wolfley, and sideline reporting from Paul Calvisi. Spanish-language broadcasts are carried on KQMR / KHOV “Latino Mix”, featuring Luis Hernández and former Cardinals lineman Rolando Cantú. Fans can also follow coverage through the Arizona Sports app (iOS / Android) or listen directly on the Cardinals’ “On the Air” page.
San Francisco 49ers Radio
In the Bay Area, the 49ers’ English-language broadcasts are carried by KNBR 680 AM and KSAN 107.7 The Bone. Guy Haberman will handle play-by-play in 2025, with longtime analyst Tim Ryan providing commentary. Fans can listen via the 49ers Game Broadcast page or through the 49ers official app (iOS / Android) for mobile streaming. Spanish-language coverage for the 2025 season has not been confirmed — check 49ers.com closer to game day for updates.
National and digital options
Fans outside the local markets have national audio alternatives. SiriusXM NFL Radio offers both teams’ radio feeds as well as NFL Radio on Channel 88, with pricing at $12.99/month for streaming-only or $17.99/month for car + app access. Another option is NFL+, which provides live audio of every NFL game nationwide, including Cardinals vs 49ers, for $6.99/month.
How to watch Arizona Cardinals vs San Francisco 49ers out of market
CBS Sunday Afternoon games like Cardinals vs 49ers are regional broadcasts, not nationwide telecasts. That means only the Phoenix and Bay Area home markets are guaranteed local coverage on their CBS affiliates – KSAZ FOX 10 Phoenix and KTVU FOX 2 San Francisco. Fans outside those regions may receive a different matchup depending on FOX’s regional assignments.
For US fans outside the home markets, the official option is NFL Sunday Ticket, available as a standalone subscription on YouTube or bundled with YouTube TV. Pricing for new subscribers starts around $276 for the season (or eight monthly payments of about $34.50).
- Local blackout rules apply: if the game is already airing on your local CBS or FOX station, it will not appear on Sunday Ticket. The service is supported on most devices, including smart TVs, Roku, Fire TV, Apple TV, PlayStation, Xbox, mobile apps, and web browsers.
Outside the US, fans can subscribe to NFL Game Pass International, which is distributed through DAZN and, in some regions, Amazon Prime Video. The package streams every NFL game live, including playoffs and the Super Bowl, and also includes NFL Network and NFL RedZone. Pricing depends on the country of purchase, and access is geo-restricted to regions outside the US.
Travelers with an active subscription can still use it abroad with a VPN. For more details, see our guide on how to watch out-of-market NFL games with a VPN.
Another popular option is NFL RedZone. While it does not provide a full game feed, it offers live look-ins and every touchdown from across all Sunday Afternoon matchups, including scoring plays from Cardinals vs 49ers. NFL RedZone is available as an add-on through major live TV streaming services such as YouTube TV, Hulu + Live TV, and Fubo.
